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TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control Alternate transcriptional splice variants

SKU: 75788465987

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USD185.00 USD223.00

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TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control Alternate transcriptional splice variantsSerine threonine protein kinase tousled like 1 encoded by TLK1 is a serine threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript

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Description

Alternate transcriptional splice variants

and domains V

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

Angiopoietin-1 encoded by ANGPT1 is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation

which results in aberrant splicing

TLK1 Polyclonal Antibody, 50ul[BT-AP09054] Thermal Control Alternate transcriptional splice variantsSerine threonine protein kinase tousled like 1 encoded by TLK1 is a serine threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript

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