MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging Mutations in this gene result

Mutations in this gene result in autosomal recessive spastic paraplegia

being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation

Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions

The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds

This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF)

MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging Mutations in this gene resultThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate and activates IkappaB kinase alpha and beta and is found to be involved in the transcription activity of NF kappaB mediated by Rho family GTPases