PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Ran-dependent mechanism

Ran-dependent mechanism

Mutations in GJA1 have been associated with oculodentodigital dysplasia

Defects in TMEM237 are a cause of Joubert syndrome-14

and serve to maintain the integrity of the extracellular matrix

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins

PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Ran-dependent mechanismMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma