EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Several transcript variants are resulted

Several transcript variants are resulted from alternative splicing of SIRT2

|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells

and acts both as a dioxygenase and as a peroxidase

GAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer

The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712)

EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Several transcript variants are resultedThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.