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CD177 Polyclonal Antibody, 100ul Vacuum Aspirator Chitobiase is a lysosomal glycosidase

SKU: 77358949695

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CD177 Polyclonal Antibody, 100ul Vacuum Aspirator Chitobiase is a lysosomal glycosidaseCD177 encodes a glycosyl phosphatidylinositol (GPI) linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule 1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary

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Description

Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda

Group II includes GRM2 and GRM3

The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers

Several transcript variants encoding multiple isoforms have been described

They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone

CD177 Polyclonal Antibody, 100ul Vacuum Aspirator Chitobiase is a lysosomal glycosidaseCD177 encodes a glycosyl phosphatidylinositol (GPI) linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule 1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary

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