Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter Involved in protein trafficking

Involved in protein trafficking

but their full-length natures have not been determined

MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes

This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

A pseudogene COX17P has been found on chromosome 13

Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter Involved in protein traffickingMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.