IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification for the liver- and erythocyte-specific

for the liver- and erythocyte-specific isoforms

Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers

Among its related pathways are Signaling by GPCR and A-beta Pathways: uptake and Degradation

the encoded protein may increase the viability of certain cell types through modulation of p53 activity

Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1

IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification for the liver- and erythocyte-specificIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.