4E-BP1 Polyclonal Antibody, 100ul[BT-AP00038] Culture Tubes and Fuchs endothelial corneal dystrophy

and Fuchs endothelial corneal dystrophy

It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor

The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation

The specific ligand of this receptor is CCL25

May play a role in tumor invasiveness and metastasis formation

4E-BP1 Polyclonal Antibody, 100ul[BT-AP00038] Culture Tubes and Fuchs endothelial corneal dystrophyEIF4EBP1 encodes one member (eukaryotic translation initiation factor 4E binding protein 1) of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is