SH2D3 Polyclonal Antibody, 100ul Miscellaneous The gene encoding DHRS2 maps

The gene encoding DHRS2 maps to human chromosome 14

GO annotations related to this gene include nucleotide binding and 5-nucleotidase activity

which are both disorders of the peripheral nervous system

This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins

Proteolytic processing is required to generate a mature subunit

SH2D3 Polyclonal Antibody, 100ul Miscellaneous The gene encoding DHRS2 mapsThis gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.