JAZF1 Rabbit Polyclonal Antibody, 50ul Dry Bath This family includes microtubule-dependent molecular

This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division

and may be involved in the function of helper T cells

The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors

An important paralog of this gene is ZC3H4

AFF1has been shown to promote the expression of CD133

JAZF1 Rabbit Polyclonal Antibody, 50ul Dry Bath This family includes microtubule-dependent molecularThis gene encodes a nuclear protein with three C2H2 type zinc fingers and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized