Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser Belongs to the PAR6 family

Belongs to the PAR6 family

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway

Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts

This gene is part of a cluster of MMP genes on chromosome 11

skeletal muscle encoded by ACTA1 belongs to the actin family of proteins

Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser Belongs to the PAR6 familyMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.