Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Participates in bidirectional cell-cell contact
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Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Participates in bidirectional cell-cell contactAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone
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