PS-1 Polyclonal Antibody, 100ul Protein Post-translational Modification The expression of this gene

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking

This PTP possesses an extracellular region

alternative products:Experimental confirmation may be lacking for some isoforms

This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X

PS-1 Polyclonal Antibody, 100ul Protein Post-translational Modification The expression of this geneAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.