PC-PLD2 Polyclonal Antibody, 100ul Cellular Function Assays Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different protein isoforms have been described

The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D)

and regulates tissue-specific alternative splicing in metazoa

Alternative splicing results in multiple transcript variants encoding the same isoform

Aberrant expression of this gene in adult tissues is associated with tumorigenesis

PC-PLD2 Polyclonal Antibody, 100ul Cellular Function Assays Three alternatively spliced transcript variantsThe protein encoded by PLD2 (phospholipase D2) catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5 bisphosphate and ADP ribosylation factor 1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and or regulated secretion. Two transcript variants