NFκB-p105(Phospho Ser907) Polyclonal Antibody, 20ul Sampling Tubes Ran-dependent mechanism

Ran-dependent mechanism

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins

The encoded protein interacts with specifc DNA structures including nicked Holliday junctions

|Contains 2 EGF-like domains

Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction

NFκB-p105(Phospho Ser907) Polyclonal Antibody, 20ul Sampling Tubes Ran-dependent mechanismThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and