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PTEN Polyclonal Antibody, 20ul[BT-AP07473] Organelle Studies Alternative splicing of this gene

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PTEN Polyclonal Antibody, 20ul[BT-AP07473] Organelle Studies Alternative splicing of this genePTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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Description

Alternative splicing of this gene results in two transcript variants that encode the same protein

Allelic variants of GABBR2 (gamma-aminobutyric acid type B receptor subunit 2) have been associated with nicotine dependence

Mutations in FGF23 are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)

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and exists as four alternatively spliced isoforms

PTEN Polyclonal Antibody, 20ul[BT-AP07473] Organelle Studies Alternative splicing of this genePTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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