p27(Phospho Ser10) Polyclonal Antibody, 20ul Vector Construction The existence of isoform Alpha

The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis

This gene encodes a member of the E1 ubiquitin-activating enzyme family

this protein was able to induce pseudopodia formation

and is thought to be required for DNA replication from viral origin of replication

The encoded protein is rich in hydrophobic amino acids such as glycine and proline

p27(Phospho Ser10) Polyclonal Antibody, 20ul Vector Construction The existence of isoform AlphaThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from