Rat Aggrecan Core Protein, ACAN ELISA Kit, 96T Liquid Handling Plays a role in the

Plays a role in the activation of NF-kappa-B mediated by IL1B

to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed: 21949356

and is similar to several known polo-like kinase kinases

Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals

This gene encodes a member of the polycystin protein family

Rat Aggrecan Core Protein, ACAN ELISA Kit, 96T Liquid Handling Plays a role in theThis proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.