LPL Monoclonal Antibody, 50ul Electronic Pipette Mutations in this gene cause

Mutations in this gene cause ovarian dysgenesis type 1

as their activation can be triggered by calcium influx and oxidative stress

HOXC6 belongs to the homeobox family

suggesting a role in leukemogenesis

Four transcript variants encoding the same protein have been identified for this gene

LPL Monoclonal Antibody, 50ul Electronic Pipette Mutations in this gene causeLPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand bridging factor for receptor mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.