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PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 100ul[BT-AP11859] Funnels Defects in this factor lead

SKU: 92464833726

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SEK141.00 SEK186.00

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PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 100ul[BT-AP11859] Funnels Defects in this factor leadPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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Description

Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality

and H subunits

An important paralog of this gene is ZIC3

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases

The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P

PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 100ul[BT-AP11859] Funnels Defects in this factor leadPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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