Porcine Caspase-3, CASP3 ELISA Kit, 96T Cell Culture Plates May act as a modulator

May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity

Gene Ontology (GO) annotations related to this gene include 4 iron

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity

Binds to endothelial cells via integrin alpha-V/beta-3 (ITGAV:ITGB3)

An important paralog of this gene is AATK

Porcine Caspase-3, CASP3 ELISA Kit, 96T Cell Culture Plates May act as a modulatorInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.