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Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets The TRRAP/TIP60 complex acetylates nucleosomal

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Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets The TRRAP/TIP60 complex acetylates nucleosomalComponent of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium

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Description

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed: 30580966)

Binds to integrin ITGAV:ITGB3 (PubMed: 28302677)

spleen and testis

but is upregulated upon activation of lymphocytes

Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets The TRRAP/TIP60 complex acetylates nucleosomalComponent of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium

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