PACE1 Rabbit Polyclonal Antibody, 20ul Isothermal Amplification Alternatively spliced transcript variants have

Alternatively spliced transcript variants have been found

and phospholemman

Defects in this gene lead to metachromatic leucodystrophy (MLD)

Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade

The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis

PACE1 Rabbit Polyclonal Antibody, 20ul Isothermal Amplification Alternatively spliced transcript variants haveThis gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C terminal domain of ezrin an ERM protein and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms.