IMMT Polyclonal Antibody, 50ul Thermo Mix The protein encoded by this

The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase

4-trisphosphate 5/6-kinase family

and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children

The encoded protein is thought to be involved in muscle relaxation

The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4

IMMT Polyclonal Antibody, 50ul Thermo Mix The protein encoded by thisComponent of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354, PubMed: 25781180).