GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging May be required for tumorigenesis

May be required for tumorigenesis of a subset of gastric adenocarcinomas

Forms a complex with NFKBIB and NF-kappa-B heterodimer (p50/NFKB1 and p65/RELA)

3) associated with gonadal dysgenesis and XY sex reversal

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains

AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging May be required for tumorigenesisGPR139 encodes a member of the rhodopsin family of G protein coupled receptors. The G protein coupled receptor 139 is almost exclusively expressed in the central nervous system. L tryptophan and L phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.