TTL Rabbit Polyclonal Antibody, 100ul Custom Peptide Synthesis from the calnexin cycle

from the calnexin cycle

and a related protein

an important step in mucin-type biosynthesis

It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs

and has been found to be overexpressed in 10% of clear cell renal carcinomas

TTL Rabbit Polyclonal Antibody, 100ul Custom Peptide Synthesis from the calnexin cycleTTL is a cytosolic enzyme involved in the posttranslational modification of alpha tubulin (see MIM 602529). Alpha tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al. 2003