Factor I Polyclonal Antibody, 100ul Cryogenic Vials E3 ubiquitin protein ligase) encodes

E3 ubiquitin protein ligase) encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and

The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix

a member of the histidine triad gene family

and distribution of the membrane-associated alpha subunit in kidney and intestine

Defects in this gene are a cause of macular corneal dystrophy (MCD)

Factor I Polyclonal Antibody, 100ul Cryogenic Vials E3 ubiquitin protein ligase) encodesCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an