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Caspase-3 Polyclonal Antibody, 100ul[BT-AP01199] Metabolic enzymes |PTM:Phosphorylated on tyrosines by ZAP-70

SKU: 97113466265

4.1
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Caspase-3 Polyclonal Antibody, 100ul[BT-AP01199] Metabolic enzymes |PTM:Phosphorylated on tyrosines by ZAP-70CASP3 encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9,

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Description

|PTM:Phosphorylated on tyrosines by ZAP-70 upon TCR activation| or by SYK upon other immunoreceptor activation

and may be involved in TP53 induced apoptosis

Two transcript variants encoding different isoforms have been found for CLEC6A

and this DMR is commonly found in imprinted genes and correlates with transcript expression

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis

Caspase-3 Polyclonal Antibody, 100ul[BT-AP01199] Metabolic enzymes |PTM:Phosphorylated on tyrosines by ZAP-70CASP3 encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9,

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