PARL Monoclonal Antibody, 50ul Miscellaneous and two NADP(+)-dependent isocitrate dehydrogenases

and two NADP(+)-dependent isocitrate dehydrogenases

UBFD1 (Ubiquitin Family Domain Containing 1) is a Protein Coding gene

Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma

2002 [PubMed 11923475])

it interacts with the three DNA-binding proteins of the shelterin complex

PARL Monoclonal Antibody, 50ul Miscellaneous and two NADP(+)-dependent isocitrate dehydrogenasesThis gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.