Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma and also controls the stability

and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins

families of heteromeric G proteins

Gene Ontology (GO) annotations related to this gene include death receptor binding

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma and also controls the stabilityMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.