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J Cell Physiol 182:163170 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson S (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

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In the sixth study (119), the 25 or 50 mg/day initial doses of topiramate were followed by respective weekly increments of 25 or 50 mg/day until the target dose of 200 mg/day was reached