NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Marked reduction in this protein

Marked reduction in this protein has been observed in association with Alzheimer's disease

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

a pseudogene of this gene has been found on chromosome 8

the protein-glutamine gamma-glutamyltransferase 2 is the autoantigen implicated in celiac disease

has not yet been determined

NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Marked reduction in this proteinThis gene encodes a member of the calcium cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone brain exchanger that can mediate a light induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury.