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91 Several studies have reported a positive relationship between insulin resistance, obesity and increased serum resistin in mouse models as increased resistin plasma levels were observed in diet-induced and ob/ob obese mice, anti-resistin antibodies increased insulin sensitivity in obese and insulin-resistant animals, healthy mice treated with recombinant resistin exhibited reduced glucose tolerance and insulin action, and resistin dampened insulin-induced glucose uptake in mouse adipocytes

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May 1994;19(5):1124-1132

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Furthermore, by interfering with folate metabolism and the one-carbon cycle, B 12 deficiency raises homocysteine levels and risks of related health problems

When administered under professional supervision, glutathione therapy is generally well tolerated