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Mechanism of Action: The Pan-Agonist

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However, it is unclear why genistein upregulates the levels of Nrf2 in the myocardium

Given the ongoing interest in antioxidants and glutathione in particular as potential therapeutic targets in depression, we have undertaken a meta-analysis to summarise current work in this field and to highlight the contribution of glutathione to the antioxidant theory of depression

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[1] [4] For patients with diabetes, additional monitoring for diabetic retinopathy is recommended, and those on insulin or sulfonylureas may require dose adjustments to prevent hypoglycaemia