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10.1146/annurev.biochem.73.011303.073940 123 WanJ.MaL.JiaoX.DongW.LinJ.QiuY.et al (2024)

TJs localised at the apex of the lateral membrane of IECs are often referred to as apical junction complexes and are composed of the apical-most TJs, adhesion junctions and desmosomes, each of which are involved in the separation of apical and basolateral membrane domains and maintaining gut barrier integrity (Turner and Turner 2010

These biomarkers can be used in adjunct to MTT assay for a more accurate prediction of the in vivo response