Homoharringtonine - CAS# 26833-87-4 spladib) (2013) Nat Chem Biol

(2013) Nat Chem Biol

Chemical Name: 18-Hydroxy-3-methoxy-2-methyl-4-methylamino-(2R

Raynaud FI

and is mainly used in the treatment of asthma and stroke

InChi: InChI=1S/C26H21N3O2S/c1-31-22-8-5-19-15-21(4-3-20(19)16-22)25-24(17-11-13-27-14-12-17)28-26(29-25)18-6-9-23(10-7-18)32(2)30/h3-16H

Homoharringtonine - CAS# 26833-87-4 spladib) (2013) Nat Chem BiolHomoharringtonine, or Omacetaxine mepesuccinate, is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML). It is a natural product first discovered in Cephalotaxus harringtonia, now manufactured by hemi synthesis. It was approved by the US FDA in October 2012 for the treatment of adult patients with CML with resistance and or intolerance to two or more tyrosine kinase inhibitors (TKIs). Product information