WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

7(10):e45539

Chemical Name: (S)-N-(bis(4-fluorophenyl)methyl)-1-(2-(2-ethyl-2-isobutyramidobutanamido)-5-guanidinopentanamido)cyclopentanecarboxamide

InChiKey: CDJNNOJINJAXPV-UHFFFAOYSA-N

Each library contains 2 or 5 mg of listed compounds in that category in separated vials in DMSO at the concentration of 10 mM or in solid format

WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamideWDR5 0103, CAS No. 890190 22 4, is a potent and selective WD repeat containing protein 5 (WDR5) antagonist with Kd of 450 nM. It has no effect on a panel of seven other methyltransferases, including SETD7. It binds in the WDR5 peptide binding pocket and inhibits the catalytic activity of the MLL core complex in vitro. WDR5 0103 is a good chemical probe to demonstrate inhibition of an important protein protein interaction and form the basis for further