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XL147-II Size:2mg solid Atherosclerosis

SKU: 16890373128

4.1
USD104.12 USD140.12

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XL147-II Size:2mg solid AtherosclerosisXL147 II is an ATP competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation in HER2+ cells and also inducing the expression and phosphorylation of HER3 and other RTKs. Product information CAS Number: 956958 53 5 Molecular Weight: 448. 52 Formula: C21H16N6O2S2 Synonym: XL147 derivative II Chemical Name: N [3 (2, 1, 3 Benzothiadiazol 5 ylamino) 2 quinoxalinyl] 4 methyl benzenesulfonamide Smiles:

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Description

Atherosclerosis

HG-10-102-01 was intraperitoneally (IP) dosed to mice at 50 mg/kg once per day

BLT2 promotes the invasion and metastasis of aggressive bladder cancer cells through a reactive oxygen species-linked pathway

It brings about near complete degradation of TBK1 in mutant K-Ras and wild-type cancer cell lines with no significant effect of proliferation

Sharlow ER

XL147-II Size:2mg solid AtherosclerosisXL147 II is an ATP competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation in HER2+ cells and also inducing the expression and phosphorylation of HER3 and other RTKs. Product information CAS Number: 956958 53 5 Molecular Weight: 448. 52 Formula: C21H16N6O2S2 Synonym: XL147 derivative II Chemical Name: N [3 (2, 1, 3 Benzothiadiazol 5 ylamino) 2 quinoxalinyl] 4 methyl benzenesulfonamide Smiles:

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