Vadimezan (DMXAA) lase SNIPER(ER)-87 is a potent and

SNIPER(ER)-87 is a potent and selective estrogen receptor α (ERα) Degrader (Specific and Nongenetic IAP-dependent Protein Erasers or SNIPER) (DC50 = 3 nM)

Molecular Weight: 458

is a novel potent and selective inhibitor of secreted frizzled-related protein-1 (sFRP-1) with an IC50 ~ 0

InChi: InChI=1S/C22H14FN5/c1-11-17(15-10-12(23)6-7-16(15)26-11)22-27-20-13-4-2-8-24-18(13)19-14(21(20)28-22)5-3-9-25-19/h2-10

and also limited connective tissue ingrowth

Vadimezan (DMXAA) lase SNIPER(ER)-87 is a potent andVadimezan, also known as DMXAA and ASA404, is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti tumor activity of tumor associated macrophages. Product information CAS Number: 117570 53 3 Molecular Weight: 282. 29