AHU-377 - CAS# 149709-62-6 scidin-Analog-1 ²⁶]nonacosa-8

²⁶]nonacosa-8

but failed to do it in rats on a normal calcium diet

Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel

Formula: C33H33N3O15

Formula: C26H37ClN2O5

AHU-377 - CAS# 149709-62-6 scidin-Analog-1 ²⁶]nonacosa-8Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Product information