MDV-3100 - CAS# 915087-33-1 60135 genome replication

genome replication

Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases

Pizarro JG

unfolded protein accumulation leads to activation of the endoplasmic reticulum transmembrane kinase/endoRNase (RNase) IRE1α

Senisterra G

MDV-3100 - CAS# 915087-33-1 60135 genome replicationEnzalutamide, also known as MDV3100, CAS No. 915087 33 1, is an orally bioavailable, organic, non steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation