AZD-7762 - CAS# 860352-01-8 Catalog No.:M10890-2 Formula: C9H7ClFN5O2

Formula: C9H7ClFN5O2

InChiKey: DGHHQBMTXTWTJV-BQAIUKQQSA-N

This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs)

Asaraldehyde is produced in both cultured broths

(Formulation: 10% dimethylacetamide in 10% Kolliphor HS15 in PBS)

AZD-7762 - CAS# 860352-01-8 Catalog No.:M10890-2 Formula: C9H7ClFN5O2AZD 7762 is a synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity. AZD7762 binds to and inhibits Chks, which may prevent cell cycle arrest and subsequent nucleotide excision repair in DNA damaged tumor cells, resulting in tumor cell apoptosis. This agent may enhance the cytotoxicity of DNA damaging agents. Chks are protein kinases that regulate either G1 S or G2 M transitions in the cell cycle. In