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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 prevents the macropinocytic uptake of

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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 prevents the macropinocytic uptake ofHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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Description

prevents the macropinocytic uptake of filoviral particles

483(7390):479-83

Martindale C

3-30 μM) significantly reduces both inward and outward components of IClCa

AGC activity is also dramatically decreased in AT13148-administrated HGC27 tumors

HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 prevents the macropinocytic uptake ofHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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