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Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine

Storage and Handling Requirements To safeguard the complex molecular bonds and prevent structural degradation of the 6mg lyophilized cake, all vials must be stored long-term in a freezer environment at -20C, completely shielded from light and ambient humidity

Why is monitoring B12 levels important

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Genetic factors may also play a role