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Pazopanib Hydrochloride Catalog No.:M10929-2 Hammond LA

SKU: 4101665552

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Pazopanib Hydrochloride Catalog No.:M10929-2 Hammond LAPazopanib HCl (GW786034 HCl) is a novel multi target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c Kit and c Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell free assays, respectively. Pazopanib induces autophagic Type II cell death. Product information CAS Number: 635702 64 6 Molecular Weight: 473. 98 Formula: C21H24ClN7O2S Chemical Name: 5 ({4 [(2,3 dimethyl 2H indazol 6 yl)(methyl)amino]pyrimidin 2 yl}amino) 2

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Description

Hammond LA

also known as ONO 5046

translation and DNA synthesis in sensitive cells (HCC4017 and H292 cells) but not insensitive cells (HBEC30KT cells and HCC44 cells)

mice) shows improved efficacy (regression) in a 92

Z433927330 blocked aquaglyceroporin H2O2 permeability

Pazopanib Hydrochloride Catalog No.:M10929-2 Hammond LAPazopanib HCl (GW786034 HCl) is a novel multi target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c Kit and c Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell free assays, respectively. Pazopanib induces autophagic Type II cell death. Product information CAS Number: 635702 64 6 Molecular Weight: 473. 98 Formula: C21H24ClN7O2S Chemical Name: 5 ({4 [(2,3 dimethyl 2H indazol 6 yl)(methyl)amino]pyrimidin 2 yl}amino) 2

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