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A BMI of 27 or higher with at least one weight-related health condition (such as high blood pressure or high cholesterol)

Vitamin B6 (P5P) Required for neurotransmitter balance and detoxification pathways

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Increase by 0.25 mg every 4 weeks to maintenance 2.4 mg (up to 4.5 mg possible)

Despite these physiological effects, there has been ongoing uncertainty about whether to hold these drugs before elective procedures