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While GLP-1 receptor agonists such as the branded Ozempic and Mounjaro have helped revolutionise weight management, the downside of rapid weight loss is the potential to lose significant muscle mass, which can lead to diminished strength and a reduced metabolism

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In this study, we observed significantly higher expression levels of mitochondrial complex I and supercomplex I in the M9a haplogroup compared to the M7/8 haplogroup under hypoxic conditions, leading to enhanced mitochondrial function and increased oxygen utilization, as evidenced by elevated OCR, MMP, and ATP production

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Factors such as disease severity, age, and comorbidities may influence the effectiveness of PRP in these patients