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AG-490 Catalog No.:M7639-2 Long-Yun P

SKU: 48063600992

4.5
USD90.00 USD127.00

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AG-490 Catalog No.:M7639-2 Long-Yun PTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8

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Description

Long-Yun P

Molecular Weight: 328

with IC50 values ranging from 13 nM to 160 nM

Chemical Name: 2-Chloro-4-[(1R

WAY-202041

AG-490 Catalog No.:M7639-2 Long-Yun PTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8

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