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Human Lysyloxidase Homolog 2, LOXL2 ELISA Kit , 96T Microbial Genome Editing Mutations in this gene cause

Human Lysyloxidase Homolog 2, LOXL2 ELISA Kit , 96T Microbial Genome Editing Mutations in this gene cause

Name: Human Lysyloxidase Homolog 2, LOXL2 ELISA Kit , 96T Microbial Genome Editing Mutations in this gene cause
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SKU: 16419440375
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SKU: 16419440375

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Human Lysyloxidase Homolog 2, LOXL2 ELISA Kit , 96T Microbial Genome Editing Mutations in this gene causeMediates the post translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (PubMed: 27735137). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys 4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (PubMed: 27735137). Shows no activity against histone H3 when it is trimethylated on 'Lys 9' (H3K9me3) or

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Description

Mutations in this gene cause nemaline myopathy type 3

tissue differentiation

subunit:Oligomerizes and associates with TNKS

and its alternative splicing generates 2 transcript variants

CAGE (cancer-associated gene protein)

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