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Simvastatin inhibits activation of nadph oxidase/p38 mapk pathway and enhances expression of antioxidant protein in parkinson disease models

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IAA inhibits dopamine levels in cerebellar Purkinje cells (Salamon et al., 2020)

Drugs that may induce CYP may also decrease the effectiveness of statins by increasing their clearance

In summary, while the existing evidence points toward a beneficial role for GA in liver disease, the consistent positivity should be interpreted with caution, likely reflecting a combination of genuine therapeutic activity, methodological limitations, and publication bias